Tpl2 Kinase Inhibitor (Synonyms: c-Cot Kinase Inhibitor, MAP3K8 Kinase Inhibitor, Tumor Progression Locus 2 Kinase Inhibitor) |
Catalog No.GC45067 |
Tpl2 Kinase Inhibitor (Compound 1) is a potent and selective Tpl2 (COT kinase, MAP3K8) inhibitor, plays an important role in the regulation of the inflammatory response and the progression of some cancers.
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Cas No.: 871307-18-5
Sample solution is provided at 25 µL, 10mM.
Tpl2 kinase inhibitor is a reversible inhibitor of tumor progression locus 2 (Tpl2; pIC50 = 7.3). It blocks LPS-induced TNF-α production in mice and human monocytes. Tpl2 kinase inhibitor has been used to evaluate the role of this enzyme in the proliferation and differentiation of cancer cells.
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(Based on Reviews and 39 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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