Triacsin C (Synonyms: FR 900190, WS 1228A) |
| Catalog No.GC10685 |
Inhibitor of acyl-CoA synthetase
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 76896-80-5
Sample solution is provided at 25 µL, 10mM.
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Triacsin C (WS 1228A), a natural intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, is from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity[1]. Triacsin C is found to be highly effective against rotavirus replication[2].
References:
[1]. Dechandt CRP, et al. Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr. 2017 Oct;49(5):399-411.
[2]. Kim Y, et al. Novel triacsin C analogs as potential antivirals against rotavirus infections. Eur J Med Chem. 2012 Apr;50:311-8.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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