Withanolide B |
| Catalog No.GC45158 |
Withanolide B is a withanolide that has been found in W.
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Cas No.: 56973-41-2
Sample solution is provided at 25 µL, 10mM.
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Withanolide B is a withanolide that has been found in W. somnifera. Unlike withanolide A, it does not increase glucose uptake in L6 myotubes. In in silico docking studies, withanolide B was identified as a neuronal nitric oxide synthase (nNOS) inhibitor (Ki = 5.15 nM), that also inhibited inducible NOS (iNOS) and endothelial NOS (eNOS; Kis = 15.48 and 66.59 nM, respectively), and as a ligand for the PARP1 catalytic domain with an estimated Ki value of 7.54 nM.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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