Z-IETD-AFC (Synonyms: Z-Ile-Glu-Thr-Asp-7-amino-4-Trifluormethylcoumarin) |
| Catalog No.GC45181 |
Z-IETD-AFC is a fluorogenic substrate for caspase-8 and granzyme B.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 219138-02-0
Sample solution is provided at 25 µL, 10mM.
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Z-IETD-AFC is a fluorogenic substrate for caspase-8 and granzyme B. Upon enzymatic cleavage by caspase-8 or granzyme B, 7-amino-4-trifluoromethylcoumarin (AFC) is released and its fluorescence can be used to quantify caspase-8 or granzyme B activity. AFC displays excitation/emission maxima of 380/500 nm, respectively.
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