Fmoc-Arg-OH.HCl is an Fmoc-protected arginine derivative. Fmoc-Arg-OH.HCl is commonly used as a building block in peptide synthesis, especially in solid-phase peptide synthesis (SPPS), for the preparation of peptides, peptide analogs, and related conjugates containing the Arg sequence[1][2].
References:
[1] Fantoni T, Orlandin A, Di Stefano I, et al. Solid phase peptide synthesis using side-chain unprotected arginine and histidine with Oxyma Pure/TBEC in green solvents. Green Chem. 2024;26(21):10929-10939.
[2] Alhassan, Mahama et al. “Revisiting NO2 as Protecting Group of Arginine in Solid-Phase Peptide Synthesis.” International journal of molecular sciences vol. 21,12 4464. 23 Jun. 2020.
















