JWH 018 N-(5-hydroxypentyl) β-D-Glucuronide-d5

JWH 018 N-(5-hydroxypentyl) β-D-glucuronide-d₅ contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 018 N-(5-hydroxypentyl) β-D-glucuronide by GC- or LC-mass spectrometry (MS). JWH 018 is a potent, synthetic cannabinoid which has been identified in herbal blends and incense.^1,2 JWH 018 N-(5-hydroxypentyl) β-D-glucuronide is a major urinary metabolite of JWH 018.^3,4

1.AuwÄrter, V., Dresen, S., Weinmann, W., et al.'Spice' and other herbal blends: Harmless incense or cannabinoid designer drugs•J. Mass Spectrom.44(5)832-837(2009) 2.Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y.Survey of current trends in the abuse of psychotropic substances and plants in JapanLeg. Med. (Tokyo)13(3)109-115(2011) 3.Sobolevsky, T., Prasolov, I., and Rodchenkov, G.Detection of JWH-018 metabolites in smoking mixture post-administration urineForensic Sci. Int.200(1-3)141-147(2010) 4.Purandare, A.V., Wan, H., and Huynh, T.N.Heterocyclic inhibitors of protein arginine methyl transferases11/403,7901-70(2006)