Cyclooxygenase

11-dehydro-2,3-dinor Thromboxane B2 (11-dehydro-2,3-dinor TXB2) has been identified as a TXB2 metabolite in human urine by GC/MS.

Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2.

11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency.

Fluprostenol isopropyl ester is a potent F-series prostaglandin receptor agonist prodrug that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma.

Fluprostenol isopropyl ester is a potent F-series prostaglandin receptor agonist prodrug that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma.

13,14-dihydro PGF1α is a potential metabolite of PGF1α.

The metabolism of F series prostaglandins (PGs), including PGF1α and PGF2α, commonly begins with the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs.

13,14-dihydro-15-keto tetranor-Prostaglandin F1β is a major urinary metabolite of PGE2 that is excreted in guinea pig urine at a concentration range of 1.34-2.74 μg/kg.

Prostaglandin E1 (PGE1) is produced by the metabolism of dihomo-γ-linolenic acid (DGLA) by the cyclooxygenase pathway.

Fluprostenol isopropyl ester is a potent F-series prostaglandin receptor agonist that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma.

19(R)-Hydroxylated prostaglandins occur in μg/ml concentrations in the semen of certain mammalian species, especially primates.

Arbaprostil (15(R)-15-methyl prostaglandin E2) is a synthetic prostaglandin E2 (PGE2) analog developed for its cytoprotective activity.

15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15.

15(R)-Prostaglandin I2 (15(R)-PGI2) is an isomer of the natural 15(S) prostanoid, PGI2.

15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor.

15-deoxy-δ12,14-Prostaglandin J2 Glutathione (15-deoxy-δ12,14-PGJ2 Glutathione) is a non-enzymatic adduct formed from 15-deoxy-δ12,14-PGJ2 and glutathione.

Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals.

L'ester isopropylique de 15-céto-fluprosténol (ester isopropylique de 15-céto-fluprosténol) est un métabolite du travoprost.

15-keto Treprostinil is an impurity found in treprostinil, which is a stable analog of prostaglandin I2 with a longer plasma half-life.

Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug.

Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds.

16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life.

The p-(p-acetamidobenzamido) phenyl ester is a crystalline derivative of 16,16-dimethyl PGE2 and a potential prodrug.

16-phenoxy PGF2α is a metabolically stable analog of PGF2α.