N-Nitrososarcosine-d3 is intended for use as an internal standard for the quantification of nitrososarcosine by GC- or LC-MS. N-Nitroso sarcosine is a nitrosamine.1 It has been found in smoked and cured meats and tobacco smoke.2,3 Dietary administration of N-nitroso sarcosine (0.25%) induces tumors in mice and administration via the drinking water at doses of 100 or 200 mg/kg induces tumors in rats.1
1.IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans: Some N-nitroso compounds(1978) 2.Herrmann, S., Duedahl-Olesen, L., and Granby, K.Occurrence of volatile and non-volatile N-nitrosamines in processed meat products and the role of heat treatmentFood Control48163-169(2015) 3.Report on carcinogens, fourteenth edition(2016)