Neuropeptides

Endomorphin 2 (trifluoroacetate salt) est un agoniste de haute affinité et hautement sélectif du récepteur μ-opioïde (K i = 0.69nM).

Endothelin-1 is a peptide vasoconstrictor and agonist of endothelin (ET) receptors ETA and ETB (IC50s = 0.15 and 0.12 nM, respectively).

Endothelin-2 is a peptide vasoconstrictor and ligand for the endothelin (ET) receptors ETA and ETB (Kbs= 32.8 and 1.33 nM, respectively).

Endothelin-3 is a peptide vasoconstricter and a ligand of the endothelin (ET) receptors ETA and ETB (Kbs = 1.05 and 1.49, respectively).

Galanin is a neuropeptide with diverse biological activities.

Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R).

Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R).

Gonadotropin-releasing hormone II (GnRH II) is a peptide agonist of the GnRH receptor (GnRHR).

Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release.

Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release.

Melanin-concentrating hormone (MCH) is an endogenous hypothalamic neuropeptide hormone that is an agonist at MCH receptors.

Met-Enkephalin is an endogenous neuropeptide involved in nociception and an agonist of δ- and μ-opioid receptors (Kis = 0.65 and 1.7 nM, respectively).

N-Acetyl ACTH (1-17) is an N-terminal peptide fragment of adrenocorticotropic hormone (ACTH), a peptide hormone found in the brain that is involved in the biological stress response.

Neurokinin A is a peptide agonist of the neurokinin-2 (NK2) receptor.

Neurokinin B is a tachykinin peptide agonist of the neurokinin-3 receptor (NK3; Ki = 0.8 nM).

Neuromedin B (NMB) is a peptide agonist of the NMB receptor (Ki = 7.4 nM in NCI-H1299 small cell lung cancer cells expressing the human receptor).

Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin, somatostatin, and amylase in rats.

Neuromedin S is a neuropeptide expressed in brain.

Neuromedin S is a neuropeptide agonist of the neuromedin U (NMU) receptors that increases calcium concentrations in CHO cells overexpressing NMU1 and NMU2 (EC50s = 65 and 91 pM, respectively).

Neuropeptide W-23 (NPW23) is an endogenous neuropeptide ligand for the orphan G protein-coupled receptors GPR7 and GPR8 (Kis = 31.8 and 20.7 pM, respectively).

Neuropeptide Y (NPY) (1-24) is an N-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion.

Neuropeptide Y (NPY) (13-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion.

Neuropeptide Y (NPY) (3-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion.

Neuropeptide Y (NPY) is a neuropeptide abundantly distributed throughout the central and peripheral nervous systems that plays a major role in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion.