Antiparasitics

Anacardic acid diene is a polyunsaturated form of anacardic acid that has been found in cashew nut shell liquid.

2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication (IC50 = 0.3 μM in Huh-7 human hepatoma cells) that is not cytotoxic at concentrations up to 100 μM.

Cardol diene is a phenol found in cashew nut shell liquid.

Cardol triene is a phenol found in cashew nut shell liquid that competitively and irreversibly inhibits mushroom tyrosinase (IC50 = 22.5 μM).

Le pénicolinate A est un dérivé de l'acide picolinique.

Methylcardol triene is a phenol found in cashew nut shell liquid that inhibits α-glucosidase (IC50 = 39.6 μM).

La (R)-(-)-melléine est un antibiotique isolé des fluides de culture de cet Aspergillus.

L'éther diméthylique d'asterriquinol D est un métabolite fongique qui peut inhiber les lignées cellulaires de myélome de souris NS-1 avec une CI50 de 28 μg/mL.

La 19,20-époxycytochalasine C, une cytochalasine, est un métabolite fongique de Nemania sp.

La 19,20-époxycytochalasine D, une cytochalasine, est un métabolite fongique de Nemania sp.

5-hydroxy Thiabendazole (5-OH TBZ) is a major metabolite of the anthelmintic thiabendazole.

Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a.

Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a.

Le cambendazol est l'un des agents les plus efficaces pour le traitement de la strongyloÏdose humaine et de la .

Clindamycin sulfoxide is an active metabolite of the antibiotic clindamycin.

DDD85646 est un inhibiteur puissant de N-myristoyltransférase de Trypanosoma brucei (NMT), présente une valeur d'IC50 de 2nM contre NMT de T. brucei NMT (TbNMT) et de 4nM contre NMT humain (hNMT).

Deethylindanomycin is a polyether antibiotic that has been found in S.

Diacetylcercosporin is a perylenequinone produced by Cercospora and Septoria that has diverse biological activities.

Doramectin aglycone is an acid degradation product of doramectin, a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectin monosaccharide.

Doramectin monosaccharide is an acid degradation product of doramectin, a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes.

Drimentine A is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria.

Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.

Febrifugine is a quinazolinone alkaloid originally isolated from D.

FR900098 is a derivative of fosmidomycin that has antimalarial activity (IC50s = 170, 170, and 90 nM for HB3, A2, and Dd2 P.