GLPBio

Guanylate Cyclase

GC (guanylyl cyclaese) converts GTP into cGMP and pyrophosphate. sGC (soluble GC) is a nitric oxide receptor and pGC (transmembrance GC) is a natriiuritic peptide receptor. Its major functions include cell hyperplasia,hypertrophy, cell differentiation and tumor progression etc.

Products Related to Guanylate Cyclase (29)

  • GC65449 structure
    GC65449Praliciguat
    CAS: 1628730-49-3
    Purity: >98.00%

    Praliciguat (IW-1973) est un stimulateur de guanylate cyclase soluble puissant et actif par voie orale, améliore la signalisation du NO, agit comme un vasodilatateur.

  • GC68741 structure
    GC68741BAY-747
    CAS: 1609342-18-8
    Purity: >98%

    BAY-747 (BAY 1165747) is a soluble guanylate cyclase (sGC) stimulator that is orally effective and has brain penetration. BAY-747 reverses L-NAME-induced memory impairment and enhances cognition in rats. It also lowers conscious blood pressure in both normotensive and spontaneously hypertensive rats (SHR). Additionally, BAY-747 improves skeletal muscle function related to Duchenne muscular dystrophy (DMD) in the mdx/mTRG2 mouse model.

  • GC69277 structure
    GC69277Indusatumab
    CAS: 1497400-26-6
    Purity: >95.00%

    Indusatumab (anticorps monoclonal 5F9) est un anticorps monoclonal anti-GUCY2C humain (guanylate cyclase 2C).

  • GC74357 structure
    GC74357Dolcanatide
    CAS: 1092457-65-2
    Purity: >99.00%

    Dolcanatide est un agoniste oral actif GC-C (guanylate cyclase-C).

  • GC74390 structure
    GC74390Guanylin (mouse, rat) (TFA)
    Purity: >95.00%

    Guanylin (mouse, rat) (TFA), un petide, est composé de 15 acides aminés.