2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine (16:0-18:1 PS (POPS) free acid) is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes [1] [2].
References:
[1]. Silin, V.I., and Hoogerheide, D.P. pH dependent electrical properties of the inner- and outer- leaflets of biomimetic cell membranes. J. Colloid Interface Sci. 594, 279-289 (2021).
[2]. Yu, M., Dorsey, K.H., Halseth, T., et al. Enhancement of anti-inflammatory effects of synthetic high-density lipoproteins by incorporation of anionic lipids. Mol. Pharm. 20(11), 5454-5462 (2023).
References:
[1]. Silin, V.I., and Hoogerheide, D.P. pH dependent electrical properties of the inner- and outer- leaflets of biomimetic cell membranes. J. Colloid Interface Sci. 594, 279-289 (2021).
[2]. Yu, M., Dorsey, K.H., Halseth, T., et al. Enhancement of anti-inflammatory effects of synthetic high-density lipoproteins by incorporation of anionic lipids. Mol. Pharm. 20(11), 5454-5462 (2023).