GLPBio

5-Iodoindolin-2-one

Catalog No.: GC80158Purity:>99.00%Synonyms: 5-iodo-2,3-dihydro-1H-indol-2-one
COASDSData Sheet
5-Iodoindolin-2-one (5-iodo-2,3-dihydro-1H-indol-2-one) is an intermediate that can be used in the synthesis of degraders, such as KRAS degrader-1 [1].

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

5-Iodoindolin-2-one
Cas No.: 193354-13-1
10mM (in 1mL DMSO)In Stock
$23.00
1
100mgIn Stock
$21.00
1
500mgIn Stock
$38.00
1
1gIn Stock
$49.00
1
5gIn Stock
$86.00
1
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引用文献 (Citations)

現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
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    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

5-Iodoindolin-2-one (5-iodo-2,3-dihydro-1H-indol-2-one) is an intermediate that can be used in the synthesis of degraders, such as KRAS degrader-1 [1].

In Vitro, 5-Iodoindolin-2-one (Compound a) is an intermediate that can be used in the synthesis of degraders[1].

References:
[1]. Wei Xiaofeng, et al. A selective mTORC1 degrader based on the autophagy-lysosome pathway and its preparation method and application. CN119462690A. 2026-02-06

製品資料 (Product Documents)

Purity:>99.00%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
193354-13-1
同義語
5-iodo-2,3-dihydro-1H-indol-2-one
分子式
C8H6INO
分子量
259.05
溶解性
DMSO: 100 mg/mL (386.03 mM; Need ultrasonic)
保存条件
Store at 4°C, protect from light
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

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