A-796260 is a synthetic cannabinoid (CB) that shows high selectivity for the CB2 receptor (Ki = 0.77 nM) over the CB1 receptor (Ki = 2,100 nM).[1] It also shows efficacy in vivo in models of inflammatory, post-operative, neuropathic, and osteoarthritic pain, activities which are selectively blocked by CB2 receptor-selective antagonists.[2] This product is intended for research and forensic uses.
Reference:
[1]. Poso, A., and Huffman, J.W. Targeting the cannabinoid CB2 receptor: Modelling and structural determinants of CB2 selective ligands. British Journal of Pharmacology 153(2), 335-346 (2008).
[2]. Yao, B.B., Hsieh, G.C., Frost, J.M., et al. In vitro and in vivo characterization of A-796260: A selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models. British Journal of Pharmacology 153(2), 390-401 (2008).