GLPBio

ACC1/2-IN-2

Catalog No.: GC27870Purity:>99.00%
COASDSData Sheet

ACC1/2-IN-2 (compound PF-3) is a potent ACC1/2 inhibitor with IC50 values of 22 and 48 nM for ACC1 and ACC2, respectively.

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

ACC1/2-IN-2
Cas No.: 1031411-94-5
5mgIn Stock
$182.00
1
10mgIn Stock
$292.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

引用文献 (Citations)

現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

ACC1/2-IN-2 (compound PF-3) is a potent ACC1/2 inhibitor with IC50 values of 22 and 48 nM for ACC1 and ACC2, respectively. ACC1/2-IN-2 has antiproliferation activity and can be used for cancer research[1].

References:
[1]. Wei Q, et al. Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors. Bioorg Chem. 2020 Aug;101:103943.

製品資料 (Product Documents)

Purity:>99.00%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
1031411-94-5
化学名
Spiro[2H-1-benzopyran-2,4'-piperidin]-4(3H)-one, 6,7-dimethyl-1'-[(7-methyl-1H-indazol-5-yl)carbonyl]-
SMILES
O=C1CC2(CCN(C(C3=CC4=C(NN=C4)C(C)=C3)=O)CC2)OC5=CC(C)=C(C)C=C15
分子式
C24H25N3O3
分子量
403.47
保存条件
-20°C
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

Reviews

Review for ACC1/2-IN-2

Rating: 5
  • 5 Star100%
  • 4 Star0%
  • 3 Star0%
  • 2 Star0%
  • 1 Star0%