Bisnoralcohol is a RANKL inhibitor with an IC50 of 2.325 μM. Bisnoralcohol can inhibit RANKL-induced osteoclastogenesis and exhibits antiosteoporosis activity [1].
References:
[1]. Zhang DJ, et al. Synthesis of Heterocyclic Ring-Fused Bisnoralcohol Derivatives as Novel Small-Molecule Antiosteoporosis Agents. J Med Chem. 2024 May 23;67(10):8271-8295.
References:
[1]. Zhang DJ, et al. Synthesis of Heterocyclic Ring-Fused Bisnoralcohol Derivatives as Novel Small-Molecule Antiosteoporosis Agents. J Med Chem. 2024 May 23;67(10):8271-8295.
















