BSPOTPE is the mixture of (E)-BSPOTPE and (Z)-BSPOTPE. BSPOTPE binds Human serum albumin (HSA), exhibits aggregation-induced emission (AIE) phenomenon. BSPOTPE shows selectivity for albumin (such as HSA and BSA), but has no obvious fluorescence response to other proteins and DNA. BSPOTPE can be used as fluorescent probe for HSA [1].
References:
[1]. Hong Y, et al., Quantitation, visualization, and monitoring of conformational transitions of human serum albumin by a tetraphenylethene derivative with aggregation-induced emission characteristics. Anal Chem. 2010 Aug 15;82(16):7035-43.
References:
[1]. Hong Y, et al., Quantitation, visualization, and monitoring of conformational transitions of human serum albumin by a tetraphenylethene derivative with aggregation-induced emission characteristics. Anal Chem. 2010 Aug 15;82(16):7035-43.