CPPD-Q (Synonyms: CPPD-quinone) |
カタログ番号GC91673
One-Click Copy Product Info
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CPPD-Q is an oxidized derivative of the antioxidant CPPD, possessing antibacterial and insecticidal effects.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 68054-78-4
Sample solution is provided at 25 µL, 10mM.
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CPPD-Q is an oxidized derivative of the antioxidant CPPD, possessing antibacterial and insecticidal effects. CPPD-Q exhibits toxicity to Vibrio fischeri (EC50=6.98mg/L). CPPD-Q exerts its insecticidal effect by inducing the production of reactive oxygen species (ROS) in the intestine of Caenorhabditis elegans. CPPD-Q can be used in research related to antibacterial agents and insecticides[1-4].
References:
[1] Wang W, Chen Y, Fang J, et al. Toxicity of substituted p-phenylenediamine antioxidants and their derived novel quinones on aquatic bacterium: Acute effects and mechanistic insights. J Hazard Mater. 2024 May 5;469:133900.
[2] Wang Y, Liang G, Chao J, et al. Comparison of intestinal toxicity in enhancing intestinal permeability and in causing ROS production of six PPD quinones in Caenorhabditis elegans. Sci Total Environ. 2024 Jun 1;927:172306.
[3] Fu Z, Mao W, Qu J, et al. Mitochondrial DNA copy number mediates PPD-Qs-induced lipid level alterations in humans. Ecotoxicol Environ Saf. 2026 Apr 1;314:120047.
[4] Zhang S, Zhou Z, Wang P, et al. Oxidative damage induced by daily exposure to primary and emerging aromatic amines: Insights from large scale biomonitoring and cell-based high-throughput PCR array analysis. J Hazard Mater. 2025 Sep 15;496:139300.
| Cas No. | 68054-78-4 | SDF | |
| 同義語 | CPPD-quinone | ||
| Formula | C18H20N2O2 | M.Wt | 296.4 |
| 溶解度 | Acetonitrile: Slightly Soluble: 0.1-1 mg/ml | Storage | -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.3738 mL | 16.8691 mL | 33.7382 mL |
| 5 mM | 674.8 μL | 3.3738 mL | 6.7476 mL |
| 10 mM | 337.4 μL | 1.6869 mL | 3.3738 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)