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DCM–ONOO

カタログ番号GC80343 Copy One-Click Copy Product Info

DCM-ONOO is a near-infrared two-photon fluorescence probe specifically designed for real-time monitoring of the dynamic fluctuations of peroxynitrite (ONOO⁻) in epilepsy models.

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DCM–ONOO 化学構造

Cas No.: 2759816-87-8

サイズ 価格 在庫数 個数
1mg
$86.00
在庫あり
5mg
$214.00
在庫あり
10mg
$338.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


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Sample solution is provided at 25 µL, 10mM.



Description of DCM–ONOO

DCM-ONOO is a near-infrared two-photon fluorescence probe specifically designed for real-time monitoring of the dynamic fluctuations of peroxynitrite (ONOO⁻) in epilepsy models. DCM-ONOO exhibits excellent optical properties, with a single photon excitation (Ex) of 520 nm; a single photon emission (Em) of 685 nm; a two-photon excitation of 820 nm; and a Stokes shift of 165 nm. When DCM-ONOO is combined with ONOO⁻, it shifts from 460 nm to 512 nm, and only generates a significant fluorescence response to ONOO⁻. DCM-ONOO has been successfully applied to rat epilepsy models [1].

References:
[1]. Luo X, et al. Indication of Dynamic Peroxynitrite Fluctuations in the Rat Epilepsy Model with a Near-Infrared Two-Photon Fluorescent Probe. Anal Chem. 2021 Feb 2;93(4):2490-2499.

Chemical Properties of DCM–ONOO

Cas No. 2759816-87-8 SDF
Formula C32H22N3O2P M.Wt 511.51
溶解度 DMSO: 5.45 mg/mL (10.65 mM; Need warming) Storage Store at 4°C, away from moisture and light
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of DCM–ONOO

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1 mg 5 mg 10 mg
1 mM 1.955 mL 9.775 mL 19.55 mL
5 mM 391 μL 1.955 mL 3.91 mL
10 mM 195.5 μL 977.5 μL 1.955 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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