Ebselen Oxide (Synonyms: NSC 639772) |
| カタログ番号GC43584 |
エブセレンのセレノン類似体である酸化エブセレンは、ジグアニル酸シクラーゼ (DGC) を共有結合的に修飾して、c-ジ-GMP 受容体相互作用を阻害し、DGC 活性を低下させます。
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Cas No.: 104473-83-8
Sample solution is provided at 25 µL, 10mM.
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Ebselen is an excellent scavenger of peroxynitrite and is used for the treatment of cerebral infarctions. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, indicating that it can serve as a negative control for ebselen.[1]
Reference:
[1]. Lass, A., Witting, P., Stocker, R., et al. Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: Antioxidant actions in addition to hydroperoxide-reducing activity. Biochimica et Biophysica Acta 1303, 111-118 (1996).
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