Swertiajaponin |
| カタログ番号GC37707 |
Swertiajaponin はチロシナーゼ阻害剤であり、チロシナーゼの結合ポケットと複数の水素結合および疎水性相互作用を形成し、IC50 は 43.47 μM です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6980-25-2
Sample solution is provided at 25 µL, 10mM.
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Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1]. IC50: 43.47 μM (tyrosinase)[1]
[1]. Lee B, et al. Swertiajaponin inhibits skin pigmentation by dual mechanisms to suppress tyrosinase. Oncotarget. 2017 Sep 15;8(56):95530-95541.
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