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4-Amino-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical

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4-Amino-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical 化学構造

Cas No.: 14691-88-4

サイズ 価格 在庫数 個数
25g
$30.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.



Description of 4-Amino-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical

4-Amino-TEMPO can be used as a spin label for detecting radicals and the damage caused by them. 4-Amino-TEMPO possesses superoxide dismutase-mimetic activity, enabling it to easily penetrate cells and protect them from oxidative damage induced by H2O2. Additionally, 4-Amino-TEMPO exhibits significant radiation protective properties, effectively safeguarding DNA from oxidative stress-induced damage caused by UV exposure due to its ability to maintain a positive charge. Furthermore, 4-Amino-TEMPO is a highly selective oxidation catalyst widely used in the research and development of various specialty chemicals, including fragrances, pesticides, and others .

[1]. Żamojć K, Zdrowowicz M, Hać A, et al. Dihydroxy-substituted coumarins as fluorescent probes for nanomolar-level detection of the 4-amino-TEMPO spin label[J]. International journal of molecular sciences, 2019, 20(15): 3802. 

Chemical Properties of 4-Amino-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical

Cas No. 14691-88-4 SDF
Formula C9H19N2O M.Wt 171.26
溶解度 Storage -20°C argon filling
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 4-Amino-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 5.8391 mL 29.1954 mL 58.3908 mL
5 mM 1.1678 mL 5.8391 mL 11.6782 mL
10 mM 583.9 μL 2.9195 mL 5.8391 mL
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**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

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In vivo Formulation Calculator (Clear solution) of 4-Amino-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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