2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddATP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.
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製品資料 (Product Documents)
Purity:>90.00%Appearance:A solid
化学的性質 (Chemical Properties)
純度
>90.00%
吸光係数
15,400 Lmol-1cm-1 at 258 nm
分子式
C10H16N5O10P3S (free acid)
M.Wt
491.20 g/mole (free acid)
塩形
Li+
濃度
100 mM
緩衝液
H2O
保存条件
-20°C or below
同義語
Alpha Thiol ddATP, 1-Thio-ddATP
バックボーン
5'-O-(1-Thiotriphosphate)
塩基類似体
Adenosine
糖の種類
2'-3'-Dideoxy
ヌクレオチド分類
Phosphate Modified
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