ホーム>>Signaling Pathways>> Microbiology & Virology>> Bacterial>>JT71

JT71

カタログ番号GC78829 Copy One-Click Copy Product Info

JT71 is an inhibitor of the transcriptional activator MrkH of type III fimbriae in Klebsiella pneumoniae.

Products are for research use only. Not for human use. We do not sell to patients.

JT71 化学構造

Cas No.: 380887-90-1

サイズ 価格 在庫数 個数
5mg
$72.00
在庫あり
10mg
$115.00
在庫あり
25mg
$207.00
在庫あり
50mg
$331.00
在庫あり
100mg
$530.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


顧客レビュー

カスタマーレビューに基づきます。

Sample solution is provided at 25 µL, 10mM.



Description of JT71

JT71 is an inhibitor of the transcriptional activator MrkH of type III fimbriae in Klebsiella pneumoniae. JT71 reduces the activity of the mrkA promoter in Klebsiella pneumoniae, effectively inhibiting the formation of biofilms by Klebsiella pneumoniae, while not affecting the cell's viability. JT71 can be used for research on Klebsiella pneumoniae infections [1].

References:
[1]. Wilksch JJ, et al. Chemical inhibition of MrkH-dependent activation of type 3 fimbriae synthesis and biofilm formation by Klebsiella pneumoniae. NPJ Biofilms Microbiomes. 2025 Nov 20;11(1):212.

Chemical Properties of JT71

Cas No. 380887-90-1 SDF
Formula C18H18N2O2S M.Wt 326.41
溶解度 DMSO: 4.17 mg/mL (12.78 mM; Need ultrasonic) Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of JT71

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.0636 mL 15.3182 mL 30.6363 mL
5 mM 612.7 μL 3.0636 mL 6.1273 mL
10 mM 306.4 μL 1.5318 mL 3.0636 mL
  • モルアリティ計算機

  • 希釈計算機

  • Molecular Weight Calculator

質量
=
濃度
x
容積
x
MW*
 
 
 
**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

計算

In vivo Formulation Calculator (Clear solution) of JT71

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

View current batch:

レビュー

Review for JT71

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%