Lipopeptide CPK4 TFA is a Cholesterol -modified peptide K4 [(KIAALKE) 3 ]. Lipopeptide CPK4 TFA is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPK4 TFA triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) and TO-PRO-3 iodide, and Doxorubicin (DOX). Lipopeptide CPK4 TFA can be used for drug delivery research [1].
References:
[1]. Yang J, et al. Drug Delivery via Cell Membrane Fusion Using Lipopeptide Modified Liposomes. ACS Cent Sci. 2016 Sep 28;2(9):621-630.
References:
[1]. Yang J, et al. Drug Delivery via Cell Membrane Fusion Using Lipopeptide Modified Liposomes. ACS Cent Sci. 2016 Sep 28;2(9):621-630.