MMA-NODAGA TFA is a chelator for site-specific labeling of targeting proteins containing unpaired cysteine. MMA-NODAGA TFA can be used to conjugate with exosome and 64 Cu in image with positron emission tomography (PET) [1] [2].
References:
[1]. Sara F F Almeida, et al. Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis. Small. 2022 Dec;18(49):e2203999.
[2]. Mohamed Altai, et al. Influence of nuclides and chelators on imaging using affibody molecules: comparative evaluation of recombinant affibody molecules site-specifically labeled with ⁶⁸Ga and ¹¹¹In via maleimido derivatives of DOTA and NODAGA. Bioconjug Chem. 2013 Jun 19;24(6):1102-9.
References:
[1]. Sara F F Almeida, et al. Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis. Small. 2022 Dec;18(49):e2203999.
[2]. Mohamed Altai, et al. Influence of nuclides and chelators on imaging using affibody molecules: comparative evaluation of recombinant affibody molecules site-specifically labeled with ⁶⁸Ga and ¹¹¹In via maleimido derivatives of DOTA and NODAGA. Bioconjug Chem. 2013 Jun 19;24(6):1102-9.