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Phenaglycodol

カタログ番号GC70247 Copy One-Click Copy Product Info

Phenaglycodolはブタンジオール類に属し、抗不安と抗痙攣作用がある。

Products are for research use only. Not for human use. We do not sell to patients.

Phenaglycodol 化学構造

Cas No.: 79-93-6

サイズ 価格 在庫数 個数
1 mg
$86.00
在庫あり
5 mg
$180.00
在庫あり
10 mg
$293.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


顧客レビュー

カスタマーレビューに基づきます。

Sample solution is provided at 25 µL, 10mM.



Description of Phenaglycodol

Phenaglycodol belongs to the group of butanediolsa with anxiolytic and anticonvulsant porperties. Phenaglycodol has orally bioactivity.

Phenaglycodol (20 mg/kg, i.p.,1 time ) has antiepileptic activity in cat[1].
Phenaglycodol (55-80 mg/kg, i.p., 1 time) has antiepileptic activity in mice[1].
Phenaglycodol (50-100 mg/kg, i.g., 1 time) has antiepileptic activity in monkey[1].
Phenaglycodol (130mg/kg, i.p., 1 time) lowers the concentration of Meprobamate in serum and brain[2].

References:
[1]. G T JONES, et al. Mode of action of phenaglycodol, a new neurosedative agent. Proc Soc Exp Biol Med. 1956 Dec;93(3):528-31.
[2]. R. KATO, et al. Induced Increase o f M eprobam ate M etabolism in R ats T reated w ith P hénobarbital or Phenaglycodol. Pharmacology (1970) 3 (2): 95–100.

Chemical Properties of Phenaglycodol

Cas No. 79-93-6 SDF
Formula C11H15ClO2 M.Wt 214.69
溶解度 Storage
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Phenaglycodol

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.6579 mL 23.2894 mL 46.5788 mL
5 mM 931.6 μL 4.6579 mL 9.3158 mL
10 mM 465.8 μL 2.3289 mL 4.6579 mL
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**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

計算

In vivo Formulation Calculator (Clear solution) of Phenaglycodol

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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レビュー

Review for Phenaglycodol

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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