Radulone A is a sesquiterpene fungal metabolite originally isolated from R. confluens that has diverse biological activities. It is active against eight bacterial strains (MICs = 41-406 µM). Radulone A inhibits ADP-, collagen-, arachidonic acid-, or phorbol 12-myristate 13-acetate-induced aggregation of isolated human platelets (IC50 = 2, 28, 53, and 38 µM, respectively). It induces cytotoxicity in L1210 skin lymphocytic leukemia, HL-60 promyeoloblast leukemia, and HeLa cervical cancer cells and COS-7 kidney fibroblasts (IC50s = 1, 2, 20, and 16 µM).
Radulone A
Catalog No.: GC92256Purity:>70.00%
Radulone A is a sesquiterpene fungal metabolite originally isolated from R. confluens that has diverse biological activities.
製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。
Cas No.: 221374-79-4
1mgIn Stock
$245.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $245.00 | In Stock | 1 |
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引用文献 (Citations)
現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
製品説明 (Description)
製品資料 (Product Documents)
Purity:>70.00%Appearance:A solid
化学的性質 (Chemical Properties)
CAS番号
221374-79-4
化学名
(3S,8aS,8bS,9S)-2,3,8,8a-tetrahydro-9-hydroxy-3,6,8a-trimethyl-3,8b-methano-8bH-cyclobuta[5,6]benzo[1,2-b]pyran-5(7H)-one
SMILES
CC(C1=O)=C2CC[C@]2(C)[C@@]34OC[C@](C)(C=C14)[C@@H]3O
分子式
C15H18O3
分子量
246.30162
溶解性
Dichloromethane: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
保存条件
-20°C
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。
計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度
g/mol
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