GLPBio

RO3244794

Catalog No.: GC27945Purity:>99.50%
COASDSData Sheet

RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pKi of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. 

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

RO3244794
Cas No.: 361457-01-4
1mgIn Stock
$213.00
1
5mgIn Stock
$531.00
1
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引用文献 (Citations)

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    641, 529–536 (2025)
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    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pKi of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. RO3244794 exhibits analgesic and anti-inflammatory potential[1].

References:

[1]. Bley KR, et, al. RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists. Br J Pharmacol. 2006 Feb;147(3):335-45. 

製品資料 (Product Documents)

Purity:>99.50%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
361457-01-4
分子式
C25H19F2NO5
分子量
451.42
溶解性
DMSO : 50 mg/mL (110.76 mM; Need ultrasonic)
保存条件
Store at 4°C, protect from light
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

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