GLPBio

SB 206553

Catalog No.: GC27944Purity:>99.00%
COASDSData Sheet

SB 206553 is a 5-HT2C inverse agonist. 

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

SB 206553
Cas No.: 158942-04-2
10mM (in 1mL DMSO)In Stock
$158.00
1
5mgIn Stock
$144.00
1
10mgIn Stock
$230.00
1
25mgIn Stock
$460.00
1
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引用文献 (Citations)

現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

SB 206553 is a 5-HT2C inverse agonist. SB 206553 can attenuate methamphetamine-seeking in rats. SB 206553 has activity for 5-HT2 receptor ligands in HEK-293 or CHO-K1 cells expressing human recombinant 5-HT2 receptors with pKi values of 5.6 nM (5-HT2A), 7.7 nM (5-HT2B) and 7.8 nM (5-HT2C), respectively. SB 206553 can be used for the research of psychostimulant abuse disorders[1].

References:
[1]. Graves SM, et al. SB 206553, a putative 5-HT2C inverse agonist, attenuates methamphetamine-seeking in rats. BMC Neurosci. 2012 Jun 14;13:65.

製品資料 (Product Documents)

Purity:>99.00%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
158942-04-2
化学名
Benzo[1,2-b:4,5-b′]dipyrrole-1(2H)-carboxamide, 3,5-dihydro-5-methyl-N-3-pyridinyl-
分子式
C17H16N4O
分子量
292.34
溶解性
DMSO : 100 mg/mL (342.07 mM; Need ultrasonic)
保存条件
-20°C, sealed storage, away from moisture
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

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