GLPBio

EAAT2

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Excitatory amino acid transporter 2 (EAAT2) is the major glutamate transporter and functions to remove glutamate from synapses. An increase in EAAT2 protein expression and function may provide a means to prevent insufficient glutamate reuptake and consequently reduce neuronal damage.

The glial glutamate transporter EAAT2 plays a major role in glutamate clearance. EAAT2 can be upregulated by transcriptional or translational activation.EAAT2 is a potential target for the prevention of excitotoxicity.

Products Related to EAAT2(6)

  • GC10875 structure
    GC10875LDN 212320
    CAS: 894002-50-7
    Purity: >98.00%

    LDN 212320 (LDN-0212320) es un activador del transportador de glutamato (GLT-1)/transportador de aminoácidos excitatorios 2 (EAAT2) (a nivel de traducción).

  • GC13659 structure
    GC13659WAY 213613
    CAS: 868359-05-1
    Purity: >99.00%

    WAY 213613 es un inhibidor de EAAT2 humano potente y selectivo.

  • GC31075 structure
    GC31075GT 949
    CAS: 460330-27-2
    Purity: >99.50%

    GT 949 es un modulador alostérico positivo del transportador de aminoÁcidos excitatorios selectivo 2 (EAAT2) con una CE50 de 0,26 nM.

  • GC38472 structure
    GC38472DL-TBOA
    CAS: 205309-81-5
    Purity: >98%

    An EAAT inhibitor

  • GC38524 structure
    GC38524WAY-213613 hydrochloride
    CAS: 2450268-84-3
    Purity: >98.50%

    WAY-213613 (clorhidrato) es un inhibidor de EAAT2 humano potente y selectivo.

  • GC64288 structure
    GC64288EAAT2 activator 1
    CAS: 892415-28-0
    Purity: >98.00%

    El activador 1 de EAAT2 es el potente activador del transportador de aminoÁcidos excitatorios 2 (EAAT2).