Sphingolipids
Products for Sphingolipids
- Cat.No. Nombre del producto Información
- GC43071 C22 Sphingomyelin (d18:1/22:0) C22 Sphingomyelin is a naturally occurring form of sphingomyelin.
- GC43072 C23 Globotriaosylceramide (d18:1/23:0) C23 Globotriaosylceramide is a sphingolipid that has been used as a standard for the quantification of globotriaosylceramides in human fibroblasts by HPLC/APCI-MS.
- GC45836 C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0/24:0) A hydroxylated dihydro ceramide
- GC45834 C24 (2'(R)-hydroxy) Phytoceramide (t18:0/24:0) A bioactive sphingolipid
- GC45835 C24 (2'(S)-hydroxy) Phytoceramide (t18:0/24:0) A sphingolipid
- GC46109 C24 1-Deoxyceramide (m18:1/24:0) A very long-chain atypical ceramide
- GC43073 C24 3'-sulfo Galactosylceramide (d18:1/24:0) C24 3'-sulfo Galactosylceramide is an endogenous sulfated glycolipid, which are also known as sulfatides.
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GC43074
C24 Ceramide (d18:1/24:0)
Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase.
- GC47005 C24 Ceramide-d7 (d18:1-d7/24:0) An internal standard for the quantification of lignoceric ceramide
- GC46110 C24 dihydro 1-Deoxyceramide (m18:0/24:0) A very long-chain atypical ceramide
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GC43075
C24 dihydro Ceramide (d18:0/24:0)
C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.
- GC43076 C24 Phytosphingosine (t18:0/24:0) C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis.
- GC46111 C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) A very long-chain atypical ceramide
- GC43077 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
- GC43078 C24:1 Ceramide (d18:1/24:1(15Z)) Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase.
- GC47006 C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) An internal standard for the quantification of nervonic ceramide
- GC45952 C24:1 dihydro 1-Deoxyceramide (m18:0/24:1) A very long-chain atypical ceramide
- GC47007 C26 Sphingomyelin (d18:1/26:0) A sphingolipid
- GC47009 C26:1 Sphingomyelin (d18:1/26:1(17Z)) A naturally occurring sphingolipid
- GC43080 C30 Ceramide (d18:1/30:0) C30 Ceramide is a naturally occurring ceramide that has been found in the stratum corneum of human and nude mouse skin.
- GC43081 C30(ω-hydroxy) Ceramide (d18:1/30:0) C30(ω-hidroxi) La ceramida (d18:1/30:0), un esfingolÍpido, es un componente vital especÍfico de la epidermis de la barrera de agua en la piel de los mamÍferos.
- GC43082 C32 Ceramide (d18:1/32:0) C32 Ceramide is a naturally occurring ceramide that has been found in the stratum corneum of human and nude mouse skin.
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GC43084
C4 Ceramide (d18:1/4:0)
C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC43086 C6 Biotin Ceramide (d18:1/6:0) C6 Ceramide-biotin is an affinity probe that allows C2 ceramide (d18:1/2:0) to be detected or immobilized through interaction with the biotin ligand.
- GC45839 C6 Biotin dihydro Ceramide (d18:0/6:0) An affinity probe for C6 dihydro ceramide binding partners
- GC49013 C6 Biotin Ganglioside GD3 (d18:1/6:0) (ammonium salt) An affinity probe for ganglioside GD3 binding partners
- GC43089 C6 Biotin Glucosylceramide (d18:1/6:0) C6 Biotin glucosylceramide is an affinity probe that allows C6 glucosylceramide to be detected or immobilized through interaction with the biotin ligand.
- GC45840 C6 Biotin Phytoceramide (t18:0/6:0) An affinity probe for C6 phytoceramide binding partners
- GC11079 C6 Ceramide (d18:1/6:0) La ceramida C6, un activador de la ruta de las ceramidas, muestra actividad contra una variedad de lÍneas de células cancerosas. La ceramida C6 se puede utilizar como adyuvante de los agentes quimioterapéuticos para potenciar los efectos antitumorales.
- GC43091 C6 Ceramide (d18:1/6:0) Alkyne C6 Ceramide alkyne is an ω-alkyne derivative of C6 ceramide.
- GC40688 C6 D-threo Ceramide (d18:1/6:0) C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM).
- GC43092 C6 dihydro Ceramide (d18:0/6:0) C6 dihydro Ceramide is a metabolically inactive analog of C6 ceramide that has been used as a negative control in experiments investigating the biological activity of C6 ceramide.
- GC47015 C6 Glucosylceramide (d18:2/6:0) A glucosylated form of C6 ceramide
- GC40689 C6 L-erythro Ceramide (d18:1/6:0) C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC40690 C6 L-threo Ceramide (d18:1/6:0) C6 L-threo Ceramide (d18:1/6:0) es un esfingolÍpido bioactivo y un anÁlogo permeable a las células de las ceramidas naturales.
- GC43096 C6 NBD Ceramide (d18:1/6:0) C6 NBD Ceramide (d18:1/6:0) es una sonda fluorescente del aparato de Golgi con permeabilidad de la membrana celular.
- GC43097 C6 NBD dihydro Ceramide (d18:0/6:0) C6 NBD dihydro Ceramide (d18:0/6:0) es un anÁlogo de esfinganina y se puede utilizar como tinte fluorescente para marcar Ácidos grasos.
- GC43098 C6 NBD Galactosylceramide (d18:1/6:0) La galactosilceramida C6 NBD es un derivado activo de la galactosilceramida que estÁ marcado con nitrobenzoxadiazol C6 fluorescente (C6 NBD).
- GC43099 C6 NBD Glucosylceramide (d18:1/6:0) C6 NBD Glucosilceramida (d18:1/6:0) es un derivado fluorescente de glucosilceramida (Ex=466 nm, Em=535 nm).
- GC43101 C6 NBD L-threo Ceramide (d18:1/6:0) C6 NBD L-threo Ceramide (d18:1/6:0) es una ceramida permeable a la membrana.
- GC43100 C6 NBD Lactosylceramide (d18:1/6:0) La lactosilceramida C6 NBD (d18:1/6:0) es un derivado de las lactosilceramidas y se puede utilizar en el ensayo de lactosilceramida sintasa como sustrato aceptor fluorescente. La lactosilceramida C6 NBD (d18:1/6:0) también se puede utilizar en la investigaciÓn del cÁncer.
- GC40774 C6 NBD Phytoceramide (t18:0/6:0) C6 NBD phytoceramide is a biologically active derivative of C6 phytoceramide that is tagged with a fluorescent C6 nitrobenzoxadiazole group.
- GC43103 C6 NBD Sphingomyelin (d18:1/6:0) La esfingomielina C6 NBD (d18:1/6:0) es un anÁlogo fluorescente de cadena corta de la esfingomielina.
- GC43104 C6 Phytoceramide (t18:0/6:0) C6 Phytoceramide is a cell-permeable analog of phytoceramide.
- GC45616 C6 Urea Ceramide An inhibitor of neutral ceramidase
- GC43106 C8 Ceramide-1-phosphate (d18:1/8:0) C8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate.
- GC43107 C8 Ceramine (d18:1/8:0) C8 Ceramine is an analog of C8 ceramide in which the carbonyl group of the ceramide is replaced by a methylene group.
- GC43109 C8 D-threo Ceramide (d18:1/8:0) C8 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC43108 C8 dihydro Ceramide (d18:0/8:0) C8 dihydro Ceramide (d18:0/8:0) es un control negativo de C8 Ceramide. C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) es un anÁlogo permeable a las células de las ceramidas naturales. C8-Ceramide tiene propiedades anti-proliferaciÓn y actÚa como un potente agente quimioterapéutico. C8-Ceramide estimula las células dendrÍticas para promover las respuestas de las células T ante las infecciones por virus. C8-Ceramide induce una ligera activaciÓn de la proteÍna quinasa (PKC) in vitro.
- GC43110 C8 Galactosylceramide (d18:1/8:0) C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids.
- GC43111 C8 L-threo Ceramide (d18:1/8:0) C8 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC43112 C8 Phytoceramide (t18:0/8:0) C8 Phytoceramide is a cell-permeable analog of phytosphingosine.
- GC18757 CAY10444 CAY10444 (BML-241) es un antagonista de la esfingosina-1-fosfato 3 (S1P3). CAY10444 inhibe en un 37 % los aumentos inducidos por S1P en Ca2+ en células HeLa que expresan receptores S1P3.
- GC40757 CAY10734 An S1P1 receptor agonist
- GC41494 CAY10739 CAY10739 es un inhibidor selectivo de S1PR1, con un pIC50 de 7,6, con una selectividad >40 y >80 veces, sobre las otras isoformas S1PR2/3/4 de S1PR.
- GC52489 Ceramide (hydroxy) (bovine spinal cord) A sphingolipid
- GC52485 Ceramide (non-hydroxy) (bovine spinal cord) A sphingolipid
- GC52486 Ceramide Phosphoethanolamine (bovine) A sphingolipid
- GC43229 Ceramide Phosphoethanolamines (bovine) Ceramide phosphoethanolamine (CPE) is an analog of sphingomyelin that contains ethanolamine rather than choline as the head group.
- GC47073 Ceramides (hydroxy) A mixture of hydroxy fatty acid-containing ceramides
- GC43230 Ceramides (non-hydroxy) Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase.
- GC47074 Cerebroside C Cerebroside C, un esfingolÍpido, es un metabolito fÚngico.
- GC45877 CYM 5478 CYM 5478 es un agonista de S1P2 potente y altamente selectivo con un EC50 de 119 nM en un ensayo de eliminación de TGFα.
- GC40296 D-erythro-MAPP D-erythro-MAPP (D-e-MAPP) es un inhibidor de ceramidasa, con un IC50 de 1-5 μM in vitro.
- GC47189 D-erythro/L-threo Lysosphingomyelin (d18:1) A mixture of bioactive sphingolipids
- GC40792 D-threo Sphinganine (d18:0) D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0).
- GC47276 D-threo-PPMP (hydrochloride) D-treo-PPMP (clorhidrato) es un potente inhibidor de la glucosilceramida (GlcCer) sintasa.
- GC49672 DL-erythro-PDMP (hydrochloride) A mixture of PDMP isomers
- GC43488 DL-erythro/threo Sphinganine (d16:0) DL-erythro/threo Sphinganine (d16:0) is a sphingolipid that is decreased in rats following long-term, low-dose administration of dimethoate and is used as a biomarker for dimethoate exposure.
- GC43494 DL-threo-PDMP (hydrochloride) DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP : D-threo (1R,2R) and L-threo (1S,2S) PDMP.
- GC47286 Eliglustat-d15 (tartrate) An internal standard for the quantification of eliglustat
- GC43615 EOS (d18:1/30:0/18:2) EOS is a ceramide found in the outer layer of the epidermis in mammals.
- GC43616 EOS (d18:1/32:1/18:2) EOS is a ceramide found in the outer layer of the epidermis in mammals.
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GC40887
FTY720 (R)-Phosphate
FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.
- GC52483 Fucosylated Ganglioside GM1 (porcine) (ammonium salt) A sphingolipid
- GC52288 Fumonisin B1-13C34 An internal standard for the quantification of fumonisin B1
- GC18469 Galactosylcerebrosides (bovine) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with hydroxy and non-hydroxy fatty acids.
- GC43721 Galactosylcerebrosides (hydroxy) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid.
- GC43722 Galactosylcerebrosides (non-hydroxy) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid.
- GC43723 Galactosylsphingosine (d18:1) La galactosilesfingosina (d18:1) (galactosilesfingosina), un sustrato de la enzima galactocerebrosidasa (GALC), es un biomarcador potencial de la enfermedad de Krabbe.
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GC43727
Ganglioside GD1a mixture (sodium salt)
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.
- GC43728 Ganglioside GD1b Mixture (sodium salt) Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit.
- GC49490 Ganglioside GD2 Mixture (bovine buttermilk) (ammonium salt) A semi-synthetic mixture of ganglioside GD2
- GC43729 Ganglioside GD3 Mixture (sodium salt) Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases.
- GC43730 Ganglioside GM1 Asialo Mixture Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase.
- GC47392 Ganglioside GM1 Mixture (ovine) (ammonium salt) A mixture of ganglioside GM1
- GC43731 Ganglioside GM2 Asialo Mixture Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2.
- GC40016 Ganglioside GM2 Mixture (sodium salt) Ganglioside GM2 is a glycosphingolipid component of cellular membranes, primarily the plasma membrane.
- GC43732 Ganglioside GM3 Mixture (sodium salt) Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation.
- GC52487 Ganglioside GM4 (chicken egg) (ammonium salt) A sphingolipid
- GC43734 Ganglioside GQ1b Mixture (sodium salt) Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit.
- GC52505 Ganglioside GT1b (bovine) (sodium salt) A sphingolipid
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GC43735
Ganglioside GT1b Mixture (sodium salt)
Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit.
- GC43757 Globotetraosylceramides (porcine RBC) Globotetraosylceramides are bioactive neutral glycosphingolipids.
- GC52492 Globotriaosylceramide (hydroxy) (porcine RBC) A sphingolipid
- GC52491 Globotriaosylceramide (non-hydroxy) (porcine RBC) A sphingolipid
- GC43758 Globotriaosylceramides (hydroxy) (porcine) Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides.
- GC43760 Globotriaosylceramides (porcine) Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides.
- GC18387 Glucocerebrosides Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.
- GC43768 Glucocerebrosides (Gaucher's spleen) Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.