Quercetin 3-O-(6’’-O-malonyl)-β-D-glucoside

Quercetin 3-O-(6''-O-malonyl)-β-D-glucoside es un derivado del glucósido de flavonol y un glucósido acilado de quercetina ^[1]. Quercetin 3-O-(6''-O-malonyl)-β-D-glucoside tiene una excelente actividad antioxidante en un entorno libre de células, pero no ejerce el mismo efecto protector en llos sistemas biológicos ^{[2, 3]}. Quercetin 3-O-(6''-O-malonyl)-β-D-glucoside se encuentra principalmente en palntas leguminosas (como la soja y la alfafa) y algunas plantas medicinales ^[4].

References:
[1] Petrova N V, Chernonosov A A, Koval V V, et al. LC–HRMS for the identification of quercetin and its derivatives in Spiraea hypericifolia (Rosaceae) and anatomical features of its leaves[J]. Plants, 2023, 12(2): 381.
[2] Panat N A, Amrute B K, Bhattu S, et al. Antioxidant Profiling of C3 Quercetin Glycosides: Quercitrin, Quercetin 3-β-D-glucoside and Quercetin 3-O-(6”-O-malonyl)-β-Dglucoside in cell free environment[J]. Free Radicals and Antioxidants, 2015, 5(2): 90-100.
[3] Alizadeh S R, Ebrahimzadeh M A. O‐Glycoside quercetin derivatives: Biological activities, mechanisms of action, and structure–activity relationship for drug design, a review[J]. Phytotherapy Research, 2022, 36(2): 778-807.
[4] Zhang Q, Zhao X, Qiu H. Flavones and flavonols: Phytochemistry and biochemistry[M]//Natural products. Springer, Berlin, Heidelberg, 2013: 1821-1847.