GLPBio

UCM-A86

Catalog No.: GC79509Purity:>98.50%
COASDSData Sheet
UCM-A86 is a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors with EC 50 values of 21 µM and 19 µM at GluN1/GluN3A and GluN1/GluN3B receptors, respectively.

Los productos son exclusivamente para uso en investigación. No aptos para uso humano. No vendemos a pacientes.

UCM-A86
Cas No.: 1210899-51-6
10mM (in 1mL DMSO)In Stock
$143.00
1
5mgIn Stock
$130.00
1
10mgIn Stock
$207.00
1
25mgIn Stock
$409.00
1
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Citas (Citations)

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Descripción (Description)

UCM-A86 is a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors with EC 50 values of 21 µM and 19 µM at GluN1/GluN3A and GluN1/GluN3B receptors, respectively. UCM-A86 selectively potentiates responses from GluN1/GluN3A/B over GluN1/GluN2A-D receptors. UCM-A86 can be used in the research of central nervous system diseases [1].

References:
[1]. Benton AJ, et al. UCM-A86 is a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors. bioRxiv [Preprint]. 2025 Nov 16:2025.11.14.688378.

Documentos del producto (Product Documents)

Purity:>98.50%Appearance:A solid
COASDSData Sheet

Propiedades químicas (Chemical Properties)

N.º CAS
1210899-51-6
Fórmula molecular
C15H13F3N4S
Peso molecular
338.35
Solubilidad
DMSO: 100 mg/mL (295.55 mM; Need ultrasonic)
Almacenamiento
Store at 4°C, stored under nitrogen
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.

Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad

g/mol

Reviews

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