AN-2898 ia a potent and selective PDE4 inhibitor potentially for the treatment of fungal infection. AN2898 inhibited phosphodiesterase 4 (PDE4) enzyme activity (IC50 0.060 μM) and the release of multiple cytokines including TNF-α (IC50 0.16 μM) from peripheral blood mononuclear cells (hPBMCs) stimulated by lipopolysaccharide (LPS) or phytohemag- glutinin.
AN-2898
Catalog No.: GB62232Purity:>98.00%Synonyms: AN-2898; AN 2898; AN2898.
AN-2898 ia a potent and selective PDE4 inhibitor potentially for the treatment of fungal infection.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 906673-33-4
5mgIn Stock
$150.00
1
10mgIn Stock
$250.00
1
25mgIn Stock
$450.00
1
50mgIn Stock
$750.00
1
100mgIn Stock
$1,350.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5mg | $150.00 | In Stock | 1 | |
| 10mg | $250.00 | In Stock | 1 | |
| 25mg | $450.00 | In Stock | 1 | |
| 50mg | $750.00 | In Stock | 1 | |
| 100mg | $1,350.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
906673-33-4
Synonyms
AN-2898; AN 2898; AN2898.
SMILES
N#CC1=CC=C(OC2=CC=C(B(O)OC3)C3=C2)C=C1C#N
Molecular Formula
C15H9BN2O3
Molecular Weight
276.06
Solubility
Soluble in DMSO, not in water
Storage
Store at-20℃
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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