1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester is a secondary oxidized metabolite of di(isononyl) cyclohexane-1,2-dicarboxylate (DINCH), an alternative for phthalate plasticizer.
References:
[1]. Schütze A, Pälmke C, Angerer J, Weiss T, Brüning T, Koch HM. Quantification of biomarkers of environmental exposure to di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH) in urine via HPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2012;895-896:123-130.
[2]. Rodríguez-Carrillo A, Remy S, Koppen G, et al. Urinary phthalate/DINCH metabolites associations with kisspeptin and reproductive hormones in teenagers: A cross-sectional study from the HBM4EU aligned studies. Sci Total Environ. 2024;929:172426.
References:
[1]. Schütze A, Pälmke C, Angerer J, Weiss T, Brüning T, Koch HM. Quantification of biomarkers of environmental exposure to di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH) in urine via HPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2012;895-896:123-130.
[2]. Rodríguez-Carrillo A, Remy S, Koppen G, et al. Urinary phthalate/DINCH metabolites associations with kisspeptin and reproductive hormones in teenagers: A cross-sectional study from the HBM4EU aligned studies. Sci Total Environ. 2024;929:172426.
















