1',4-Dihydroxymidazolam is a hydroxylated metabolite produced by cytochrome P450 -mediated metabolism of midazolam in the liver [1].
References:
[1]. Jurica J, et al. HPLC determination of midazolam and its three hydroxy metabolites in perfusion medium and plasma from rats. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Jun 01;852(1-2):571-7.
References:
[1]. Jurica J, et al. HPLC determination of midazolam and its three hydroxy metabolites in perfusion medium and plasma from rats. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Jun 01;852(1-2):571-7.