1-Ethenylpyrene (1-Vinylpyrene) is an anti-chemical carcinogen that inhibits the formation of skin tumors initiated by either DMBA or Benzo[a]pyrene .
Application of 44 nmol of 1-Ethenylpyrene (1-Vinylpyrene) inhibits tumor initiation by 10 nmol of DMBA approximately 30%; application of 4.4 μmol of 1-Ethenylpyrene (1-Vinylpyrene) inhibits tumor initiation by 200 nmol of Benzo[a]pyrene approximately 56%[1].
References:
[1]. W L Alworth, et al. Potent inhibitory effects of suicide inhibitors of P450 isozymes on 7,12-dimetlbenz[a]anthracene and benzo[a]pyrene initiated skin tumors. Carcinogenesis. 1991 Jul;12(7):1209-15.