Citraconimide is a 3-methylmaleimide derivative. Citraconimide has thiol affinity and can undergo highly regioselective addition with a variety of alkyl thiols. Citraconimide derivatives show growth inhibitory activity against HeLa cells. Citraconimide can be modified by N-substitution, halogenation andotherreactions for use in bioactive molecule design and drug development research[1].
References:
[1].Earl, R.A., et al. Chemical investigations of citraconimide†. Journal of Heterocyclic Chemistry, 15: 1479-1483.