High affinity anti-human ErbB2 aptamer conjugated to Janelia Fluor® 646 (Kd = 13 nM). Exhibits high affinity and specificity for ErbB2. Displays dense labeling of the stained structures. Suitable for use in super-resolution microscopy techniques. For optimal binding, aptamers require refolding into their tertiary structure prior to use. Please refer to the protocol for information regarding refolding.
Pala et al (2014) Tumor-specific hyperthermia with aptamer-tagged superparamagnetic nanoparticles. Int.J.Nanomedicine 9 67 PMID:24379664