BAY-179 is an inhibitor of mitochondrial complex I, also known as NADH dehydrogenase (IC50s = 79, 38, 27, and 47 nM for the human, mouse, rat, and dog enzymes, respectively).1 See the Structural Genomics Consortium (SGC) website for more information.
1.Mowat, J., Ehrmann, A.H.M., Christian, S., et al.Identification of the highly active, species cross-reactive complex I inhibitor BAY-179ACS Med. Chem. Lett.13(3)348-357(2022)