CGN peptide TFA is a 13 amino acid peptide composed of D-amino acids, referred to as CGN peptide. CGN peptide TFA is the retro-inverso isomer of the l-peptide TGN (TGNYKALHPHNG) and can deliver siRNA to the blood-brain barrier (BBB). CGN peptide TFA can be used in Alzheimer's disease (AD) research [1].
References:
[1]. Zheng X, et al. A hybrid siRNA delivery complex for enhanced brain penetration and precise amyloid plaque targeting in Alzheimer's disease mice. Acta Biomater. 2017 Feb;49:388-401.
References:
[1]. Zheng X, et al. A hybrid siRNA delivery complex for enhanced brain penetration and precise amyloid plaque targeting in Alzheimer's disease mice. Acta Biomater. 2017 Feb;49:388-401.