Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG)[1][2].
References:
[1]. Yu L, et al. The interaction of phospholipase A2 with phospholipid analogues and inhibitors. J Biol Chem. 1990 Feb 15;265(5):2657-64.
[2]. Trousil S. Choline Kinase Inhibition as a Treatment Strategy of Cancers with Deregulated Lipid Metabolism. Imperial College London, 2014.