cis-Vaccenic acid is an ω-7 fatty acid that has been found in mango pulp.[1] It induces differentiation of, and γ-globin synthesis in, K562 and JK-1 cells, as well as isolated sickle cell transgenic mouse bone marrow erythroid progenitor cells (TMbmEPSCs).[2]
Reference:
[1]. Shibahara, A., Yamamoto, K., Nakayama, T., et al. cis-Vaccenic acid in mango pulp lipids. Lipids 21(6), 388-394 (1986).
[2]. Aimola, I.A., Inuwa, H.M., Nok, A.J., et al. Cis-vaccenic acid induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cells. Eur. J. Pharmacol. 776, 9-18 (2016).