Cyclooxygenase

ICI 192،605 هو مضاد قوي لـ TXA2R (مستقبل الثرموبوكسان A2) كخلية تشير إلى البروستاجلاندين.

TP specific agonist

Prostaglandin B1 (PGB1) is a non-enzymatic dehydration product of PGE1 resulting from treatment with strong base.

Polmacoxib (CG100649) هو عقار مضاد للالتهابات غير ستيرويدي نشط عن طريق الفم (NSAID) وهو الأول من نوعه في فئته ، وهو مثبط مزدوج لـ COX-2 (IC50 حوالي 0.1 ميكروغرام / مل) وكربونيك أنهيدرازيمنع Polmacoxib الورم الحميد في القولون والمستقيم ونمو الورم في نماذج الفئران

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.

15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH.

بيكوتاميد هو مثبط مشترك لمركب سينسيز A2 (TxA2) ومستقبلات

A naturally occurring prostaglandin with antiviral/antitumor activity

Prostaglandin F2α methyl ester (PGF2α methyl ester) is an analog of PGF2α in which the C-1 carboxyl group has been esterified as the methyl ester.

15(S)-15-methyl PGF2α methyl ester is a derivative of 15(S)-15-methyl PGF2α with increased membrane permeability.

Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor.

Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized.

6-keto prostaglandin F1α (6-keto PGF1α) is the inactive, non-enzymatic hydrolysis product of PGI2.

Prostaglandin B2 (PGB2) is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base.

A major active metabolite of flurbiprofen

Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH).

تافلوبروست إيثيل أميد مشتق من البروستاغلاندين.

A metabolite of meloxicam

11β-Prostaglandin E1 (11β-PGE1) is an epimerized form of PGE1 at the C-11 position.

11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1.

11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.

Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin.

Microsomal Prostaglandin E2 Synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever and pain.

Pimprinine is an alkaloid originally isolated from Streptomyces that has diverse biological activities, including anticonvulsant, antiplatelet, and antimicrobial properties.