DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties [1].
In Vitro, DSPE-PEG2000-ANG functionalized liposomes significantly reduce the number of colonies formed by GL261 glioma cells[1].
References:
[1]. Qin Y, et al. Dual-Functional Nanoliposome with High BPA Loading for Targeted MRI-Guided BNCT of Glioblastoma. ACS Appl Mater Interfaces. 2025;17(37):52474-52487.
In Vitro, DSPE-PEG2000-ANG functionalized liposomes significantly reduce the number of colonies formed by GL261 glioma cells[1].
References:
[1]. Qin Y, et al. Dual-Functional Nanoliposome with High BPA Loading for Targeted MRI-Guided BNCT of Glioblastoma. ACS Appl Mater Interfaces. 2025;17(37):52474-52487.