Fmoc-His(MMt)-OH is a histidine derivative used for solid phase peptide synthesis [1]. Fmoc-His(MMt)-OH has both amino and side chain protection [2]. Fmoc-His(MMt)-OH is commonly used to synthesize peptides containing histidine [3].
References:
[1]. Barlos K, Chatzi O, Gatos D, et al. Fmoc-His (Mmt)-OH und Fmoc-His (Mtt)-OH. Zwei nue histidin-derivative Nim-geschützt mit säure-hochempfindlichen gruppen. Darstellung, eigenschaften und einsatz in der peptidsynthese. Tetrahedron letters. 1991 Jan 21; 32(4): 475-478.
[2]. Luckose F, Pandey MC, Radhakrishna K. Effects of amino acid derivativeson physical, mental, and physiological activities. Critical reviews in food science and nutrition. 2015 Nov 10; 55(13): 1793-807.
[3]. Yang Y. Green Chemistry of Minimal-Protection Solid-Phase Peptide Synthesis. InGreen Chemistry for Environmental Sustainability-Prevention-Assurance-Sustainability (PAS) Approach 2023 Aug 11. IntechOpen.