FPMINT is a potent, irreversible and non-competitive inhibitor of Equilibrative nucleoside transporters ( ENTs ), which is more selective to ENT2 than to ENT1. FPMINT plays an important role in uridine uptake [1].
References:
[1]. Renkai Li, et al. Structure-Activity Relationship Studies of 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine (FPMINT) Analogues as Inhibitors of Human Equilibrative Nucleoside Transporters. Front Pharmacol. 2022 Feb 21:13:837555.
References:
[1]. Renkai Li, et al. Structure-Activity Relationship Studies of 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine (FPMINT) Analogues as Inhibitors of Human Equilibrative Nucleoside Transporters. Front Pharmacol. 2022 Feb 21:13:837555.