Ganglioside GD3 (d18:1/12:0) is a type of glycosphingolipid, the d18:1 indicates the sphingosine base, and the 12:0 represents the fatty acid part which is lauric acid. Ganglioside GD3 (d18:1/12:0) is a crucial intermediate in the biosynthesis pathway of gangliosides and is mainly found in the brain tissues of mammals. Ganglioside GD3 (d18:1/12:0) plays significant roles in development, cell signal transduction, and various diseases [1] [2].
References:
[1]. Li TA, Schnaar RL. Congenital Disorders of Ganglioside Biosynthesis. Prog Mol Biol Transl Sci. 2018;156:63-82.
[2]. Merrill Jr AH, Sandhoff K. Sphingolipids: Metabolism and cell signaling. InNew comprehensive biochemistry 2002 Jan 1 (Vol. 36, pp. 373-407). Elsevier.
References:
[1]. Li TA, Schnaar RL. Congenital Disorders of Ganglioside Biosynthesis. Prog Mol Biol Transl Sci. 2018;156:63-82.
[2]. Merrill Jr AH, Sandhoff K. Sphingolipids: Metabolism and cell signaling. InNew comprehensive biochemistry 2002 Jan 1 (Vol. 36, pp. 373-407). Elsevier.