HSL-IN-1 |
| رقم الكتالوجGC36257 |
HSL-IN-1 (المركب 24 ب) هو مثبط قوي وفعال للليباز الحساس للهرمونات (HSL) (IC50 = 2 نانومتر) مع انخفاض كبير في مسؤولية المستقلب التفاعلي
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Cas No.: 2095156-13-9
Sample solution is provided at 25 µL, 10mM.
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HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1]. IC50: 2 nM (Hormone sensitive lipase)[1]
[1]. Ogiyama T, et al. Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation. Bioorg Med Chem. 2017 Apr 1;25(7):2234-2243.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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